The OM-PSG project investigates the role of Msr (Methionine Sulfoxide Reductase) enzymes in bacterial responses to oxidative stress. By combining fluorescence microscopy at the single-cell level with microfluidic tools, this project aims at gaining deeper insights into bacterial stress responses and repair mechanisms under oxidative conditions.
The originality of this research lies in the dynamic study of these enzymes under controlled conditions, enabling real-time observation of their role in bacterial physiology. Through the technological developments implemented, the project opens new interdisciplinary perspectives and strengthens collaborations in advanced imaging and oxidative stress biology.
This work is part of a broader effort to decipher bacterial adaptation strategies to oxidative environments and is supported by IM2B for the development of innovative approaches.